HomeMy WebLinkAboutacute-respiratory-illness-outbreak-recommendations-for-long-term-care-facilities-october-2025 Division of Communicable Disease Control and Prevention
Acute Respiratory Illness Outbreak Recommendations for
Long-Term Care Facilities
October 30, 2025
This guidance was created by the Alameda County Public Health Department (ACPHD)
and is intended for use by Long-Term Care Facilities (LTCFs) for the management and
containment of acute respiratory illness (ARI) outbreaks. More detailed guidance that
includes recommendations about prevention and planning for influenza, COVID-19
and other respiratory outbreaks is available on the California Department of Public
Health (CDPH) website.
COVID-19 outbreaks must be reported electronically to ACPHD using the instructions
found at https://covid-19.acgov.org/reporting-requirements.page. Report all
suspected or confirmed non-COVID-19 ARI outbreaks to ACPHD by calling (510) 267-
3250. To report on evenings, weekends, or holidays, call Alameda County Dispatch at
(925) 422-7595 and ask to speak with the On Call Public Health Duty Officer. Refer to
page 2 for outbreak definitions.
Please review the following documents and guidelines:
•Line List for Facilities
•Outbreak Summary Form
•Inter-Facility Infection Control Transfer Form
•CDPH Respiratory Viruses Hub
•Handwashing & Approved Disinfectants Effective Against Influenza
•Viral Respiratory Pathogens Toolkit for Nursing Homes (CDC)
•Coronavirus Disease 2019 (COVID-19) Recommendations for Personal Protective
Equipment (PPE), Resident Placement/Movement, and Staffing in Skilled Nursing
Facilities (AFL 23-12)
•Interim Work Exclusion Guidance for Healthcare Personnel with COVID-19,
Influenza, and Other Acute Respiratory Viral Infections (AFL 25-01)
•Guidance for Face Coverings as Source Control in Healthcare Settings (CDPH)
•Masking Recommendations for Staff and Visitors in Licensed Health Care Facilities
When Respiratory Viruses Circulate (ACPHD)
•Update on COVID-19 Workplace Requirements and Reminders of Guidance on
Respiratory Viruses (PIN 25-02)
Documents and other information requested by Public Health may be sent by fax to
(510) 273-3744 or secure encrypted email to AcuteCD@acgov.org
Please send the following: When to send:
Note: Privacy Rule (HIPAA) permits covered entities to disclose PHI without authorization to public
health authorities or other entities who are legally authorized to receive such reports for the purpose
of preventing or controlling disease. This includes the reporting of disease, conducting public
surveillance, investigations, or interventions.
Kimi Watkins-Tartt
Director
Public Health Department
Darlene Fujii
Director
Division of Communicable Disease
Control and Prevention
Nicholas J. Moss, MD, MPH
Health Officer
Kavita K. Trivedi, MD
Communicable Disease Controller
1100 San Leandro Blvd
San Leandro, CA 94577
(510) 267-3250
Health.AlamedaCountyCA.gov/ACPHD
Division of Communicable Disease Control and Prevention
Page 2 of 14
Acute Respiratory Illness (ARI)
Outbreak Recommendations Checklist for Facilities
Fever (oral or equivalent temperature of 100 °F or greater) and cough and/or sore throat in the absence
of a known cause other than influenza. Persons with ILI often have fever or feverishness with cough,
chills, headache, myalgia, sore throat, or runny nose. Some people, such as older persons, may have
atypical clinical presentations, including the absence of fever.
Influenza Outbreak within a LTCF
• At least one case of laboratory-confirmed influenza in the setting of a cluster (≥2 cases) of ILI
within a 72-hour period.
• Epi-linkage: Overlap on the same unit or ward, or other patient care location, or having the
potential to have been cared for by common HCP within a 72-hour time period of each other.
COVID-19 Outbreak within a LTCF
• ≥2 cases of probable or confirmed COVID-19 among residents identified within 7 days OR
• ≥3 cases of acute illness compatible with COVID-19 among residents with onset within a 72-hour
period.
• Epi-linkage: Overlap on the same unit or ward, or other patient care location, or having the
potential to have been cared for by common HCP within a 7-day time period of each other.
Non-influenza, non-COVID-19 Respiratory Outbreak within a LTCF
At least one case of a laboratory-confirmed respiratory pathogen, other than influenza or
COVID-19, in the setting of a cluster (≥2 cases) of ARI within a 72-hour period.
Acute Respiratory Illness (ARI)
An illness characterized by any two of the following: fever, cough, rhinorrhea (runny nose) or nasal
congestion, sore throat, or muscle aches.
Respiratory Outbreak of Unknown Etiology
Two or more cases of ILI or ARI occurring within 72 hours of each other without laboratory confirmation
Reporting Requirements
AND
Facilities licensed by CDPH Licensing and Certification must report outbreaks to the East Bay
District Office.
Facilities licensed by CDSS must report outbreaks to Community Care Licensing and
Certification Regional Office: (510) 286-4201 or CCLASCPOaklandRO@dss.ca.gov
Reporting to ACPHD:
Initial Reporting (non-COVID-19):
When an ILI or ARI outbreak is identified, immediately report to ACPHD at 510-267-3250, Mon-
Fri 8:30 am to 5 pm. After hours and on weekends and holidays, call Alameda County Fire
Dispatch at (925) 422-7595 and ask to speak to the On Call Public Health Duty Officer.
Submit a map/floor plan of your facility with room numbers by email to AcuteCD@acgov.org.
Complete attached Line list daily until instructed to stop for all new cases and submit
by fax to (510) 273-3744 or by secure encrypted email (AcuteCD@acgov.org) daily until
instructed to stop.
Initial Reporting (COVID-19):
See https://covid-19.acgov.org/reporting-requirements.page?
For hospitalizations and deaths, submit VEOCI hospitalization survey if directed to by
Division of Communicable Disease Control and Prevention
Page 3 of 14
After ACPHD has determined that the outbreak has resolved:
Submit a completed outbreak summary form via email (AcuteCD@acgov.org)
Outbreak Control Recommendations
Surveillance
symptoms) among all residents, health care personnel (HCP), and visitors throughout the winter
respiratory virus season or when levels of circulating virus are elevated.
Non-standard symptoms common in older adults: delirium, falls, fatigue, lethargy, low
blood pressure, painful swallowing, fainting, diarrhea, or abdominal pain.
Observe for behavior changes such as being more unsettled, expressing new delusions,
wandering more than normal, eating/drinking less than usual, or appearing sleepy.
close contact to someone with COVID-19 are not restricted from work but should follow the testing
Diagnostic and Screening Testing
If a rapid antigen (point-of-care) test
for COVID-19 or influenza is negative in a person with symptoms, obtain confirmatory testing
If RSV is circulating, consider preferential use of a molecular test that includes RSV in addition to
COVID-19 and influenza; this could include a full respiratory panel or other multiplex assay. Refer to
CDPH Weekly Respiratory Virus Dashboard for information on respiratory viruses circulating in
California. Select “Bay Area” as the region to get information on respiratory viral levels, test
Testing asymptomatic individuals exposed to COVID-19:
SNF: Test immediately (but not earlier than 24 hours after the exposure) and, if negative,
again at 3 days and if negative, again 5 days after the exposure. If unable to test on days 1, 3
and 5, proceed to Facility-wide or Group-level testing. See Appendix A for detailed
information on contract tracing and facility-wide/group-level response testing
strategies.
Non-SNF LTCF: Consider testing residents who are close contacts of someone who tested
positive for COVID-19 (e.g. roommates, dining partners, caregivers) 5 days after the
exposure.
Post-exposure testing is not generally recommended for HCP or residents who have had a
COVID-19 infection in the last 30 days, if they remain asymptomatic.
Testing asymptomatic individuals for influenza, RSV, or other non-COVID-19 respiratory
not recommended
Management Considerations for Nursing Home Residents.
Division of Communicable Disease Control and Prevention
Page 4 of 14
Communication
to notifying ACPHD and the appropriate licensing authority, notify key stakeholders including the
facility infection preventionist, administrator, medical director, health services director, staff,
residents, staff, visitors, and volunteers to report symptoms of respiratory infection to a designated
person and follow hand hygiene and respiratory hygiene/cough etiquette.
Transmission-Based Precautions, Isolation and Exclusion
Use COVID-19 PPE considerations for residents with symptoms of respiratory illness.
Precautions for COVID-19 include HCP use of a fit-tested N95 or higher-level respirator,
eye protection, gloves and gown.
Residents with symptoms of respiratory illness may remain in their current rooms with
measures in place to reduce transmission to roommates (e.g., optimizing ventilation, air
purifier, spatial separation of at least 6 feet between residents, privacy curtain between
residents).
Do not place roommates of symptomatic residents with new roommates.
Refer to Table 1 in CDPH guidance for guidance on PPE and duration of isolation for
Influenza-confirmed:
For residents who test positive for influenza and negative for COVID-19, transition to
droplet precautions. Use eye protection during procedures and patient care activities likely
to generate splashes or sprays.
Continue droplet precautions for 7 days after the resident’s illness onset or 24 hours after
the resolution of fever and improvement in respiratory symptoms, whichever is longer.
Avoid movement of residents that could lead to new exposures (e.g., roommates of
symptomatic residents, who have already been potentially exposed, should not be placed
COVID-19 confirmed
SNF residents:
o Continue transmission-based precautions for duration of 10-day isolation, even if
asymptomatic. For residents with severe/critical illness or who are
immunocompromised, follow the CDC’s Infection Control Guidance: SARS-CoV-2
o Avoid movement of residents that could lead to new exposures (e.g., roommates of
symptomatic residents, who have already been potentially exposed, should not be
placed with new roommates, if possible).
Non-SNF LTCF residents: Continue transmission-based precautions until 24 hours fever-
free (without fever-reducing medication) and respiratory symptoms are improving.
Residents should be encouraged to mask and take other precautions for 5 days after
completing isolation.
o Residents in non-SNF LTCFs should follow general CDC guidance for respiratory
illness, but facilities can consider implementing a 5-day isolation period if they
serve residents at high risk for severe COVID-19 illness.
Consider checking on residents in isolation every 4 hours for new or worsening
Division of Communicable Disease Control and Prevention
Page 5 of 14
COVID-19 exposed:
SNF Residents:
o Test immediately (but not earlier than 24 hours after the exposure) and, if negative,
again at 3 days and if negative, again 5 days after the exposure. If unable to test on
days 1, 3 and 5, proceed to Facility-wide or Group-level testing. See Appendix A
for detailed information on contract tracing and facility-wide/group-level
response testing strategies.
o Exposed contacts should continue to wear a mask when outside their room for 10
days after their exposure, even if tests are negative during that time period.
SNF Staff: For high-risk exposures, staff should test on days 1, 3 & 5 and wear high-quality
masks for source control for 10 days. For more information, see
https://www.cdc.gov/covid/hcp/infection-control/guidance-risk-assesment-hcp.html
Non-SNF LTCFs: Consider testing residents and staff who are close contacts of someone
who tested positive for COVID-19 (e.g. roommates, dining partners, caregivers) 5 days after
Cohorting:
Residents who test positive for influenza may be roomed together and residents with
COVID-19 may be roomed together unless there are other conditions present that prevent
appropriate cohorting (e.g., C. difficile, colonization with MDRO, co-infections).
o Prioritize cohorting of residents and HCP by COVID-19 status first, then by
influenza status; if necessary, designate a cohort of influenza positive residents
within a COVID-19 isolation area.
SNFs: Ensure residents with COVID-19 are promptly isolated in a designated COVID-19
isolation area. This may be a designated floor, unit, wing, or group of rooms at the end of a
unit that is physically separate and, ideally, includes ventilation measures to prevent
transmission to other residents outside the isolation area. See
https://www.cdph.ca.gov/Programs/CHCQ/LCP/Pages/AFL-23-12.aspx
Non-SNF LTCFs: Place beds as far apart as possible, when one resident is positive for
Exclusion of Ill Staff:
Exclude HCP with respiratory illness symptoms from work and have them tested for both
influenza and COVID-19.
SNF Staff: Follow CDPH’s Interim Work Exclusion Guidance for Healthcare Personnel with
COVID-19, Influenza, and Other Acute Respiratory Viral Infections
o HCP with suspected or confirmed respiratory viral infection, regardless of whether
testing is performed, should:
Not return to work until at least 3 days have passed since symptom onset and
at least 24 hours have passed with no fever (without use of fever-reducing
medicines), symptoms are improving, and they feel well enough to return to
work.
Not return to work until at least 3 days have passed since their first positive
test, even if the individual is asymptomatic throughout their infection.
Wear a face mask for source control in all patient care and common areas of
the facility (e.g., HCP breakrooms) for at least 10 days after symptom onset or
positive test (if asymptomatic), if not already wearing a facemask as part of
universal source control masking.
Non-SNF LTCF Staff:
o Staff may not return to work until afebrile >24 hours without fever-reducing
medicines and with improvement in respiratory symptoms.
o It is recommended to wear a mask for 5 days after returning to work.
Division of Communicable Disease Control and Prevention
Page 6 of 14
Infection Control Measures
Masking:
SNFs:
o Staff and visitor masking is strongly recommended in patient care areas of
SNFs during winter respiratory virus season (November 1 – March 31) and other
periods of increased respiratory virus activity.
o Masking for source control should be implemented for staff during a respiratory
illness outbreak, regardless of the time of year. See also Guidance for Face
Coverings as Source Control in Healthcare Settings.
Non-SNF LTCFs: Wearing a mask continues to be important for those who are at higher
risk for severe respiratory infections and for staff and visitors of Adult and Senior Care
facilities where higher risk individuals are present (PIN 25-02).
During an outbreak, encourage source control masking for residents while in common
Cleaning:
Increase frequency of environmental cleaning using list EPA registered list N products to at
least twice per shift with a focus on high touch surfaces and common areas.
For more information about infection control considerations for COVID-19, see the:
Improving
Ventilation Practices to Reduce COVID-19 Transmission Risk in Skilled Nursing Facilities and Best
Practices for Ventilation of Isolation Areas to Reduce COVID-19 Transmission Risk in Skilled Nursing
Keep symptomatic residents in their rooms and restrict from activities in common areas,
including meals.
Consider temporarily pausing communal dining and other group activities for all
given a shower at the end of the day with maximized ventilation. Environmental Services
Personnel and direct care staff should allow adequate time for air filtration clearance before
accessing the shower room after use and use list EPA registered list N product to clean and
disinfect the shower room before use by another resident. For more information about infection
control considerations for COVID-19, see the: https://www.cdc.gov/covid/hcp/infection-
measures using standardized adherence monitoring tools. Correct deficiencies with individual
staff, as needed, and present de-identified adherence monitoring data to staff and facility
Vaccination for Residents and Staff
Vaccines are the most effective tool for prevention of severe illness and death in LTCF
residents.
Encourage all residents and staff to stay up-to-date with vaccinations for COVID-19,
influenza, pneumococcal disease, RSV, and other recommended vaccines according to
CDPH recommendations.
Obtain standing vaccination orders from providers for residents and staff.
Vaccinate residents and staff for COVID-19 and influenza at the beginning of every
respiratory virus season, as well as newly admitted residents who are unvaccinated. Mild
illness and egg allergies are not a contraindication for receiving the influenza vaccine.
Offer the COVID-19 and influenza vaccines to residents and staff who previously
Division of Communicable Disease Control and Prevention
Page 7 of 14
Chemoprophylaxis (Influenza Only)
• Identify a supply source for rapidly obtaining antiviral chemoprophylaxis for residents and
staff.
• Define indications and processes for obtaining chemoprophylaxis, and dose adjustments as
the facility, regardless of vaccination status. If there is a limited supply of antiviral agents,
prioritize chemoprophylaxis for: 1. Roommates and residents on the same floor or unit as residents with active influenza
2. Residents in the same building with shared HCP
Consult with medical director and ACPHD for further guidance. For information about recommended
antiviral agent for at least 72 hours. Report positive results to ACPHD due to the possibility of antiviral
Track resident and staff vaccination status and calculate vaccination rates. See FAQs on Reporting
Respiratory Pathogens and Vaccination Data- March 2025 (CDC).
Identify residents who are appropriate for Pemgarda, a monoclonal antibody for moderately-to-
severely immunocompromised individuals who may not mount an adequate immune response to
COVID-19 vaccination. Pemgarda is not a substitute for vaccination and all individuals who can
Antiviral Treatment
as soon as possible, ideally within 48 hours of symptom onset, for maximum benefit.
For information about recommended influenza antiviral treatment, see CDC influenza
antiviral medication webpage.
For information about recommended COVID-19 antiviral treatment, see
https://www.cdph.ca.gov/Programs/CID/DCDC/Pages/COVID-19/Treatment-
Resources-for-Providers.aspx
o HEALTH ADVISORY: Reminder to Lower Barriers to Prescribing COVID-19
Therapeutics to Mitigate Impact of COVID-19
o IDSA Guidelines on the Treatment and Management of Patients with COVID-19
Treatment should be offered regardless of vaccination status.
Create standing orders for antiviral medication administration upon admission.
Identify a supply source for rapidly obtaining antiviral medication for residents.
Define indications and processes for obtaining antiviral agents for resident treatment.
Consult resident’s PCP for any necessary dose adjustments in persons with underlying
Do NOT wait for confirmatory test results to initiate treatment unless there is ongoing
transmission of another respiratory virus in the facility.
Antiviral agents for influenza and for COVID-19 may be administered simultaneously when
coinfection occurs.
Antiviral resistance may be possible if the resident is positive for influenza and has progressive
illness after 72 hours of treatment. Report to ACPHD and consult with PCP/medical director.
Division of Communicable Disease Control and Prevention
Page 8 of 14
Exposure to influenza occurred within 2 weeks of receiving injectable vaccine; do NOT give
antiviral chemoprophylaxis until at least 12 days after administration of intranasal live-
attenuated (LAIV) vaccine.
HCP was not vaccinated due to a medical contraindication or are at high risk for complications of
Admissions, Re-Admissions and Transferring Residents
level of care provided in an acute care setting. Hospital discharge and admission or re-admission to a
LTCF should not be delayed or prevented due to the respiratory virus status of the patient.
Implement droplet precautions for returning residents who were hospitalized with influenza and
are ready for discharge from the hospital but are still within the 7 day or longer period of required
droplet precautions.
Implement transmission-based precautions for returning residents who were hospitalized with
COVID-19 and are ready for discharge from the hospital but are still within the 10 day or longer
period of required transmission-based precautions.
See Table 1 in CDPH guidance for PPE and duration of isolation for COVID-19, influenza and RSV.
New Admissions: Do not place new admissions on units with symptomatic residents.
If a resident begins showing respiratory symptoms upon their return to the facility, place in a
single room (if available) and test the resident for influenza/COVID-19/RSV.
Do not require testing before accepting admission. Testing newly admitted, asymptomatic
residents without known exposures for COVID-19 upon arrival is an effective strategy for
identifying COVID-19 cases, when circulation is moderate or high. Refer to CDPH Weekly
Respiratory Virus Dashboard for information on respiratory viruses circulating in California.
Select “Bay Area” as the region to get information on respiratory viral levels, test positivity,
Emergency Department visits, hospital admissions and deaths in the Bay Area.
o Test on day 1, and, if negative, test again 3 days and 5 days after their admission to
inform the type of infection control precautions used (e.g., room assignment/cohorting,
or PPE) and prevent unprotected exposures.
o Use empiric transmission-based precautions pending initial test result.
o Residents who leave the facility for >24 hours should be treated as a new admission.
Asymptomatic new admissions with close contact to someone with COVID-19, regardless of
vaccination status, should be tested promptly (day 1) and, if negative, again 3 days and 5 days
admissions during an influenza or COVID-19 outbreak.
The duration of closure or limiting admissions should be determined for each
situation individually.
Facility-wide and prolonged closure are not necessary if transmission is controlled and there is
Managing Family and Visitors
• Consider implementing visitor restrictions, such as limiting the number of visitors and
excluding young children.
• Implement screening of visitors for signs of ARI and exclude symptomatic visitors.
Division of Communicable Disease Control and Prevention
Page 9 of 14
• Require universal masking for source control. • Require visitors to perform hand hygiene and follow respiratory/cough etiquette.
• Educate and encourage routine and seasonal vaccination for family and visitors. • Encourage outdoor visitation, as feasible. Avoid visitation in indoor common areas.
Nursing Home Visitation - COVID-19 (REVISED)
Assess Outbreak Control Measures
Influenza: If no new or suspected cases of influenza have been identified for at least 7 days after the
last confirmed case of influenza, it is reasonable to consider an influenza outbreak resolved and
discontinue outbreak control measures.
o When you receive notification from ACPHD that your influenza outbreak is considered
resolved, complete the Outbreak Summary form and send to ACPHD.
COVID-19:
o If using the Contact Tracing approach to testing, surveillance for new cases should
continue until there are no new positives when testing close contacts on day 1, 3 and 5 plus
5 additional days of surveillance.
o If using the Facility-wide or Unit-based approach to testing, surveillance for new cases
should continue until: 1) There are no new cases when testing on day 1, 3, and 5 plus 5
additional days of surveillance, or 2) Two consecutive weeks (14 days) of testing every 3-4
days reveals no positive test results for residents.
RSV: For RSV outbreaks, use a 10-day period after the last confirmed case to define the end of an
outbreak.
For non-influenza, non-RSV, non-COVID-19 respiratory outbreaks, resolution of the outbreak will be
determined in consultation with ACPHD. Outbreak control measures can typically be discontinued
when there have been no new cases for two median incubation periods, which varies depending on
Division of Communicable Disease Control and Prevention
Page 10 of 14
APPENDIX A
Division of Communicable Disease Control and Prevention
Page 11 of 14
Appendix A (cont.)
ALAMEDA COUNTY HEALTH Aneeka Chaudhry, Interim Agency Director
PUBLIC HEALTH DEPARTMENT Kimi Watkins-Tartt, Department Director
Division of Communicable Disease Control and Prevention Nicholas J. Moss, MD, MPH, Health Officer
1100 San Leandro Blvd Kavita K. Trivedi, MD, Communicable Disease Controller
San Leandro, CA 94577
Tel (510) 267-3250
Fax (510) 273-3744 Line List for Facilities v.10.30.2025
Name of Facility: _______________________ Today’s Date: __________ No new illness to report today
Demographics
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Comments (include any alternate diagnosis)
RESPIRATORY OUTBREAK SUMMARY FORM Facility/Organization Name: __________________________________________ Date: ____________________ Completed By: ____________________
Categories Resident Staff
Total Census Resident and Staff
# of Resident and Staff Vaccinated ≥14 Days Before
Outbreak Began
Influenza
COVID 19
Influenza Vaccine After Outbreak Began
Up COVID 19 Vaccine After Outbreak Began
# Who Received RSV Vaccine After Outbreak Began
# Not Vaccinated (Any)
# Ill Who Received Treatment (COVID 19 and/or Influenza
applicable)
Treat for COVID 19
Trea for Influenza
Ill Who Received Prophylaxis for Influenza
# of Ill Who Developed Symptoms After 72 hours of Antiviral Treatment or Chemo
prophylaxis for Influenza
# Hospitalized Influenza, COVID 19, or RSV as applicable
# of Deaths Influenza, COVID 19, or RSV
*Ill residents or staff is defined as a person who has laboratory-confirmed influenza (i.e., a positive influenza test result) OR who meets the Influenza-
Like Illness (ILI) case definition (Fever ≥100°F and cough and/or sore throat in the absence of a known cause other than influenza
Division of Communicable Disease Control and Prevention
Page 14 of 14
Handwashing and Approved Disinfectants Effective Against Influenza
Handwashing Instructions
Handwashing is the best way to prevent spreading germs to others. The proper way to wash your
hands is as follows:
• Wet your hands with clean, running water and apply soap. Use warm water if it is available.
• Lather your hands by rubbing them together with the soap. Be sure to lather the
backs of your hands, between your fingers, and under your nails.
• Scrub your hands including the palms, back of hands, between finger, and under nails.
Continue scrubbing hands for at least 20 seconds, or about the time it takes to hum the
"Happy Birthday" song from beginning to end twice.
• Rinse your hands well under clean, running water.
• Dry your hands using a clean paper towel or air dryer. If possible, use a paper towel to turn off the
faucet.
If soap and water are not available, use an alcohol-based hand sanitizer as follows:
• Apply product to the palm of one hand (read the label to learn the correct amount).
• Rub your hands together.
• Rub the product over all surfaces of your hands and fingers until your hands are dry.
More information about handwashing can be found at the CDC handwashing webpage.
Environmental Disinfection
The influenza virus can be killed by many common household and hospital-grade disinfectants, including
bleach and ammonia-based products. See the EPA List of Products Effective Against Influenza A Virus on
Hard Surfaces for a detailed list of products that are appropriate to use for cleaning and disinfection during
an influenza outbreak.