HomeMy WebLinkAboutcandida-auris-health-advisory-2023-02-23 ALAMEDA COUNTY HEALTH CARE SERVICES AGENCY Colleen Chawla, Agency Director
PUBLIC HEALTH DEPARTMENT Kimi Watkins-Tartt, Department Director
Division of Communicable Disease Control and Prevention Nicholas Moss, MD, MPH, Health Officer
1100 San Leandro Blvd Kavita K. Trivedi, MD, Communicable Disease Controller
San Leandro, CA 94577
Tel (510) 267-3250
Fax (510) 273-3744 HEALTH ADVISORY
Emergence of Candida auris in Healthcare Facilities in Northern California and Increase in Incidence of
Carbapenemase-Producing Organisms
FEBRUARY 23, 2023
SITUATION:
California Department of Public Health (CDPH) recently alerted healthcare providers to the emergence of
epidemiologically-linked Candida auris (C. auris) associated with acute care hospitals (ACH), skilled nursing
facility (SNF), and outpatient settings in Sacramento and Stanislaus counties since September 2022.
Additionally, at the end of January 2023, Alameda County Public Health Department (ACPHD) was alerted
to C. auris detection in admission screening of a patient transferred from an ACH in Contra Costa County.
These are the first reported C. auris colonizations in Northern California and none of the patients had
known exposures suggesting there is more transmission in the region than has been identified to date. In
addition, rates of Carbapenemase-producing organisms (CPO) have continued to rise across Alameda
County with many ventilator-equipped SNFs (vSNF) currently experiencing outbreaks of CPO.
Patients and residents who have had prolonged admission in healthcare settings, particularly high-acuity
care settings including LTACHs, vSNFs, high-acuity ACH units (e.g., intensive care units (ICU) and step-down
units (SDU)), are at highest risk of C. auris and other multidrug-resistant organism (MDRO) infection and
colonization. Patients should not be denied admission or transfer due to MDRO colonization. ACPHD is
committed to providing education to any healthcare providers on how to properly manage patients with
MDRO infection/colonization. ACPHD urges healthcare facilities and laboratories to implement proactive
infection prevention and control (IPC) strategies to prevent further spread of C. auris, CPO and other
MDROs.
Actions Requested of Healthcare Facilities and Laboratories:
Active Surveillance
• Assess C. auris and CPO status for all patients and residents upon admission, by reviewing medical
records and following up with the transferring facility as necessary.
• LTACHs and subacute/vSNF units should screen all patients for C. auris and CPO on admission.
• At all healthcare facilities, conduct admission screening through colonization testing for persons at
highest risk for C. auris, whose status is unknown transferring from:
1. any LTACH or vSNF ventilator unit regardless of geographic location;
2. any facility with known C. auris transmission; and
3. any ACH (in addition to any LTACH or vSNF ventilator unit) in Nevada state.
4. Consider screening patients with other known risk factors including patients receiving healthcare
outside of the US in the last 12 months or patients colonized with CPO.
• Place all patients screened on admission for C. auris and CPO on empiric Contact Precautions while
awaiting colonization testing results.
• Do not rescreen patients previously identified with C. auris and CPO; they can remain colonized
indefinitely.
• Facilities with high-risk patients such as LTACHs and vSNFs are encouraged to engage in quarterly point
prevalence surveys of both C. auris and CPO coordinated through CDPH.
• For questions or concerns regarding testing capacity for admission screenings or quarterly surveillance,
contact Acute Communicable Diseases of ACPHD at Acutecd@acgov.org.
Routine Surveillance
• Clinical and reference laboratories should identify all Candida isolates from normally sterile sites to the
species level if possible; for Candida isolated from non-sterile sites (e.g., urine), consider species-level
identification of isolates from patients at highest risk for C. auris.
• Laboratories should test Carbapenem-resistant organisms (CRO) for carbapenemase production; if
unable to perform carbapenemase testing or if isolate submission is required to comply with the
Alameda County Health Officer Order, send isolates to Alameda County Public Health Laboratory.
• Submit all C. auris and CPO isolates to Alameda County Public Health Laboratory.
• Report C. auris and CPO identification to ACPHD within one working day following instructions below.
Reporting
• C. auris and CPO identified in an Alameda County resident or patient receiving care in an Alameda
County healthcare facility are reportable within one working day of identification to Acute
Communicable Diseases of ACPHD:
• M-F 8:30-5PM call 510-267-3250 Option 2
• Afterhours and weekends call Alameda County Fire Dispatch at 925-422-7595 and ask to speak
with the on-call Public Health Duty Officer
• If C. auris or CPO is identified upon admission screening, promptly notify the referring facility.
• Communicate a patient’s C. auris, CPO, and other MDRO status to any receiving healthcare facility prior
to transfer; use an interfacility transfer form and send a copy to acutecd@acgov.org.
• Receiving facilities should proactively enquire about the patient’s status if not included in the
accompanying medical records.
Environmental Cleaning and Disinfection
• In LTACHs facility-wide, subacute/vSNF ventilator units, and ACH high-acuity units (e.g., ICU and SDU),
routinely clean and disinfect surfaces and shared medical equipment using an Environmental Protection
Agency (EPA)-registered hospital-grade disinfectant effective against C. auris from List P.
• If a List P disinfectant is unavailable, a disinfectant from List K or an appropriately-prepared bleach
solution may be used.
Infection Prevention and Control
• In all SNFs, implement Enhanced Standard Precautions now facility wide as a pre-emptive measure.
• Initiate Contact Precautions for patients with C. auris and CPO, and if possible, isolate in a single room.
• Consider C. auris, CPO and other MDRO status during room placement if and when cohorting patients
in a COVID-19 or other respiratory virus isolation area. For example, a patient with both COVID-19 and
C. auris can only be placed in the same room as another patient with COVID-19 and C. auris.
• Do NOT reuse or extend use of gloves or gowns.
• Perform hand hygiene before putting on personal protective equipment (PPE), after removing PPE, and
before and after patient contact.
• Regularly monitor healthcare personnel (HCP) adherence to IPC practices
• Continue IPC measures for the duration of a colonized or infected patient’s admission. There is no
‘clearance’ for C. auris or CPO colonization.
Antimicrobial Stewardship
• Implement antimicrobial stewardship strategies for broad-spectrum antibacterial and antifungal
agents to limit the emergence of C. auris, especially multidrug- or pan-resistant C. auris, and other
MDROs.